ARGININE METABOLISM

Review: Arginine Metabolism Revisited

Mammalian arginine metabolism is complex due to the expression of multiple enzymes that utilize arginine as substrate and to interactions or competition between specific enzymes involved in arginine metabolism. Moreover, cells may contain multiple intracellular arginine pools that are not equally accessible to all arginine metabolic enzymes, thus presenting additional challenges to more fully u...

Bacterial metabolism of arginine.

Arginine metabolism and wound healing

The dibasic amino acid arginine is of fundamental importance in wound healing as it’s metabolites nitric oxide (NO), proline, and polyamines affect all phases of the wound healing process. In the wound milieu, the concentration of arginine may decrease to undetectable levels and in this context arginine shifts from being a non-essential to a semi-essential amino acid6 as these low concentration...

Arginine Metabolism: Enzymology, Nutrition, and Clinical Significance Enzymes of Arginine Metabolism

In mammals, L-arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual. It can be derived from proline or glutamate, with the ultimate synthetic step catalyzed by argininosuccinate lyase. L-arginine is catabolized by arginases, nitric oxide synthases, arginine:glycine amidinotransferase, and possibl...

Arginine Metabolism in Developing Soybean Cotyledons

Tracerkinetic experiments were performed using L-[guanidino14C]arginine, L-[U-14C]arginine, L-[ureido-14C]citrulline, and L-[114C]omithine to investigate arginine utilization in developing cotyledons of Glycine max (L.) Merrill. Excised cotyledons were injected with carrier-free 14C compounds and incubated in sealed vials containing a CO2 trap. The free and protein amino acids were analyzed usi...